Not Just a Rash⁠

This is a 60yo lady presenting with blurred vision and floaters RE for 1 week. There’s no significant ocular history and she’s medically well besides Psoriasis. ⁠

Anterior examination revealed vision of RE 6/7.5, LE 6/6 with minor AC cells. Posteriorly she had bilateral vitritis RE>>LE. However, the most striking features were the papillitis, vasculitis and haemorrhages in the right eye. Fluorescien angiography of the RE (image 4) revealed a hot disc and vascular leakage with no evidence of non-perfusion. There was evidence of vasculitis on the left eye also (image 5). ⁠

The diagnosis of Psoriatic Uveitis was made following extensive inflammatory and infective investigations being performed.⁠

Psoriatic Uveitis may be HLAB27+ve or -ve, affects the older population, usually bilateral and has a continuous course rather than episodic recurrences. Posterior involvement is common, especially if HLAB27-ve (which our patient was). This patient responded well to systemic steroids and no further episodes have recurred.⁠

Increasing evidence of psoriasis (independent of arthropathy and HLA status) as an important cause of uveitis, particularly bilateral posterior uveitis which can be rapidly blinding. Therefore it’s important to consider psoriasis as an important cause of panuveitis. ⁠
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